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통합노출을 고려한 유해물질 관리의 우선순위 선정 KCI 등재

Prioritizing Management Ranking for Hazardous Chemicals Reflecting Aggregate Exposure

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한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
한국식품위생안전성학회 (Korean Society of Food Hygiene and Safety)
초록

In this study, we configured a system which ranks hazardous chemicals to determine their management priorities based on experts' opinions and the existing CRS (chemical ranking and scoring). Aggregate exposure of food, health functional food, oriental/herbal medicine and cosmetics have been taken into account to determine management priority. In this study, 25 hazardous chemicals were selected, such as cadmium, lead, mercury, and arsenic, etc. These 25 materials were ranked according to their 1) risk (exposure or hazard) indexes, 2) exposure source-based weight, and 3) public interests, which were also formed based on the existing priority ranking system. Cadmium was scored the highest (178.5) and bisphenol A the lowest (56.8). Ten materials -- cadmium, lead, mercury, arsenic, tar, acrylamide, benzopyrene, aluminium, benzene, and PAHs -- scored higher than 100. Eight materials -- aflatoxin, manganese, phthalate, chromium, nitrate/nitrite, ethylcarbamate, formaldehyde, and copper -- recorded scores in the range from 70 to 100. Also evaluated as potential risks were 7 materials; sulfur dioxide, ochratoxin, dioxins, PCBs, fumonisin, methyl mercury, and bisphenol A, and these materials were scored above 50. Then we compared risk index and correlation coefficient of total scores to confirm the validity of the total scores; we analyzed correlation coefficient of parameter and indicator. We discovered that the total score and weight, which has incorporated public interests, were high and statistically significant. In conclusion, the result of this study contributes to strengthening risk assessment and risk management of hazardous chemicals.

목차
ABSTRACT
 서 론
 재료 및 방법
  대상물질 선정
  화학물질의 우선순위 선정을 위한 점수체계
   노출원을 고려한 가중치
   관심도 (사회경제적 영향)
  지표와의 상관성 분석
 결과 및 고찰
  우선순위 선정 시스템 구성
   노출원을 고려한 가중치
   관심도 (사회·경제적 영향) 평가
  통합노출을 고려한 유해물질 관리의 우선순위 도출
  지표와 우선순위의 상관성 분석
 요 약
 감사의 글
 참고문헌
저자
  • 정지윤(식품의약품안전청 식품의약품안전평가원 식품위해평가부 위해분석연구과, Risk Analysis & Research Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Osong Health Technology Administration Complex) | Ji-yoon Jeong
  • 정유경(식품의약품안전청 식품의약품안전평가원 식품위해평가부 위해분석연구과, Risk Analysis & Research Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Osong Health Technology Administration Complex) | Yoo-kyung Jung
  • 황명실(식품의약품안전청 식품의약품안전평가원 식품위해평가부 위해분석연구과, Risk Analysis & Research Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Osong Health Technology Administration Complex) | Myung-sil Hwang
  • 정기경(식품의약품안전청 식품의약품안전평가원 식품위해평가부 위해분석연구과, Risk Analysis & Research Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Osong Health Technology Administration Complex) | Ki-kyung Jung
  • 윤혜정(식품의약품안전청 식품의약품안전평가원 식품위해평가부 위해분석연구과, Risk Analysis & Research Division, Food Safety Evaluation Department, National Institute of Food and Drug Safety Evaluation, Osong Health Technology Administration Complex) | Hae-jung Yoon Correspondence to