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Evaluation of the Clinical Usability of Sterile Bag Collection Urinalysis and Urine Culture for the Diagnosis of Urinary Tract Infection in Infants with Unexplained Fever

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

The study aimed to evaluate the usability of sterile bag collection (SBC) urinalysis and urine culture for diagnosing urinary tract infections (UTI). Urine culture is key for diagnosing UTI, and transurethral catheterization (TUC) or suprapubic aspiration is recommended for non-toilet-trained children. Although urine testing using SBC is non-invasive and easy, UTI can be diagnosed only if other criteria including clinical symptoms and positive urinalysis results are met. This study included 228 infants who were hospitalized for unexplained fever from October 2015 to June 2016. TUC culture, SBC urinalysis, and urine culture were performed for all patients. UTI was diagnosed when the TUC culture results met the criterion of ≥104 colony-forming units (CFU)/mL. When UTI diagnosis was made based on SBC urine colony counts ≥105 CFU/mL, the false-positive and false-negative rates were 6.3% and 70.0%, respectively. When the criterion was set as ≥104 CFU/mL, they were 23.7% and 30.0%, respectively. When both the criteria of ≥105 CFU/mL and positive urinalysis results were met, the false-positive rate was 2.4%, and the false-negative rate was 80%. Our results suggest that diagnosing UTI using SBC urinalysis and urine culture is not useful in infants with unexplained fever.

목차
Introduction
 Materials and methods
 Results
 Discussion
 References
저자
  • Ki Kang Lee(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Byeong Bae Park(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Hae In Jang(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Hyoung Min Cho(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Eun Young Kim(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Kyoung Sim Kim(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Yong Wook Kim(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Myung Hee Lee(Department of Laboratory Medicine, Kwangju Christian Hospital, Gwangju, Republic of Korea)
  • Young Kim(Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Republic of Korea) Corresponding author