Cladosiphon okamuranus is edible brown algae cultured commercially and massively at Okinawa coast. Dietary fiber occupying most of C. okamuranus isn't digested and absorbed by digestive enzymes of human. But it is known to prevent and treat constipation as metabolic disease. This study was to investigate the effects of dietary fiber extracted from C. okamuranus on the damage of liver and the blood cholesterol level in the high fat dietfed rats. The effects were measured by the levels of aspartate aminotransferase (ALT), alanine aminotransferase (AST), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) in sera. The levels of ALT, AST, TC, TG and LDL were significantly reduced in the C. okamuranus-treated group compared with the high fat diet group. But HDL level was markedly increased. The results showed that the dietary fiber extracts from C. okamuranus have the inhibitive effects of cholesterol biosynthesis in the high fat diet-fed rats.

ABSTRACT
 재료 및 방법
  실험재료
  큰실말 부산물에서의 식이섬유 추출
  실험동물 사육 및 실험식이
  혈중 HDL, LDL 함량 분석
  혈중 TC, TG 함량 분석
  혈중 AST, ALT 활성 측정
  통계처리
 결과 및 고찰
  체중의 변화
  혈액에서의 Cholesterol 수치 변화
  혈액에서의 TC, TG 수치 변화
  혈액에서의 AST, ALT 수치 변화
 결 론
 참고문헌

• 배귀정(신라대학교 의생명과학대학 생명공학과, Department of Biotechnology, College of Medical Life Science, Silla University,) | Gui-Jeong Bae Correspondence to
• 손정현(신라대학교 의생명과학대학 생명공학과, Department of Biotechnology, College of Medical Life Science, Silla University,) | Jeong-Hyeon Son
• 이재화(신라대학교 의생명과학대학 생명공학과, Department of Biotechnology, College of Medical Life Science, Silla University,) | Jae-Hwa Lee
• 정남옥(MS Global bio, MS Global Bio Co.,Ltd) | Nam-Ock Jeong
• 하배진(신라대학교 의생명과학대학 생명공학과, Department of Biotechnology, College of Medical Life Science, Silla University,) | Bae-Jin Ha