The occurrence trends and moleculargenetic characteristics of noroviruses detected from gastroenteritis patients in Jeju from 2008 to 2010 were investigated. In addition, the norovirus contamination and its characteristics of groundwaters in Jeju were examined. The incidence caused by norovirus in viral gastroenteritis patients has increased every year and was higher in male than in female. The patients caused by norovirus occurred throughout all months. The incidences started to increase from November, were very high from December to February, started to decrease from March, and were very low from June to September. The patients caused by norovirus occurred throughout all ages, however, the infants below 5 years were the most susceptible to norovirus infection and the age group from teens to forties were the most insensitive to norovirus infection. The sequencing analysis showed that 18 genotypes (8 genogroup I (GI) and 10 genogroup II (GII)) were detected, the incidences caused by GI and GII were 11.5% and 88.5%, respectively, and predominant genotype was GII-4 (70.5%), which was the major genotype giving rise to norovirus incidences in Jeju, together with GII-3 (6.1%) and GI-4 (4.1%). Among 20 groundwaters sampled at 9 wells (4 non-drinking water wells and 5 drinking water wells), noroviruses were detected from 2 groundwaters sampled at one non-drinking water well and their genotypes were GI-5 and GI-8.

Abstract
 1. 서 론
 2. 재료 및 방법
  2.1. 위장염환자의 검체 채취와 노로바이러스 RNA 추출
  2.2. 지하수 채수와 노로바이러스 RNA 추출
  2.3. 실험방법
 3. 결과 및 고찰
  3.1. 노로바이러스의 위장염환자 발생 특성
  3.2. 노로바이러스의 분자유전학적 특성
  3.3. 제주도 지하수의 노로바이러스 오염의 특성
 4. 결 론
 참 고 문 헌

• 김언주(제주특별자치도 보건환경연구원) | Yun-Joo Kim (Institute of Health & Environment, Jeju Special Self-Governing Province)
• 이민규(부경대학교 화학공학과) | Min-Gyu Lee (Department of Chemical Engineering, Pukyong National University)
• 감상규(제주대학교 환경공학과) | Sang-Kyu Kam (Department of Environmental Engineering, Jeju National University) Corresponding author