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뇌척수액 백혈구 증가증이 없는 장바이러스 뇌수막염 소아들의 임상적 특징

Clinical Manifestation of Enteroviral Meningitis without Cerebrospinal Fluid (CSF) Pleocytosis in Children

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

The aim of this study was to investigate the factors associated with cerebrospinal fluid (CSF) pleocytosis in pediatric enteroviral meningitis. A retrospective analysis of the medical records was performed in 281 patients under 18 years of age who were diagnosed with enteroviral meningitis by reverse transcription-polymerase chain reaction (RT-PCR) at Kwangju Christian Hospital from January to December 2016. Clinical symptoms and laboratory findings were compared according to the presence or absence of CSF pleocytosis. 112 children (39.9%) did not have CSF pleocytosis. When we compared the group of meningitis without pleocytosis and the group with pleocytosis, age were younger (< 2years), and the interval between onset of symptoms and the time of lumbar puncture was shorter (<24 hours), peripheral white blood cell counts were lower, but C-reactive protein (CRP) was higher in the group of meningitis without pleocytosis. Enteroviral meningitis should not be excluded even if CSF pleocytosis is not seen in patients. And enterovirus CSF RT-PCR should be performed with high suspicion in children younger than 2 years.

목차
서 론
 대상 및 방법
  통계학적 분석
 결 과
  엔테로바이러스 뇌수막염 환아들의 일반적인 특성
  연령에 따른 임상 증상의 차이
  뇌척수액 백혈구 증가증에 영향을 미치는 요인
 고 찰
 참고문헌
저자
  • 조철준(광주 기독병원 소아청소년과) | Chul Jun Cho (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 남명수(광주 기독병원 소아청소년과) | Myoung Soo Nam (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김용욱(광주 기독병원 소아청소년과) | Yong Wook Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김경심(광주 기독병원 소아청소년과) | Kyoung Sim Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 조형민(광주 기독병원 소아청소년과) | Hyung Min Cho (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김 령(광주 기독병원 소아청소년과) | Young Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 장해인(광주 기독병원 소아청소년과) | Hae In Jang (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김은영(광주 기독병원 소아청소년과) | Eun Young Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea) Corresponding author