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광물성 미네랄이 동물세포의 손상에 미치는 효과 KCI 등재

Effects of Ore Minerals on the Damages of Animal Cells

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한국환경과학회지 (Journal of Environmental Science International)
한국환경과학회 (The Korean Environmental Sciences Society)
초록

In this study, we investigated the suppressive effects of ore minerals on the allergic cell damages and oxidative cell damages. The ore minerals significantly reduced the productions of tumor necrosis factor-alpha (TNF-α) and interleukin-4 (IL-4) in rat basophilic leukemia cells challenged with 2,4-dinitrophenol-bovine serum albumin (DNP-BSA). Lipoxygenase activity was also reduced by the ore minerals. Moreover, the ore minerals showed weak protective effects on the oxidative damage induced by hydrogen peroxide in pig kidney cells and retinal ganglion cells. Photohemolysis of erythrocytes in the presence of rose-bengal as a sensitizer was also inhibited by ore minerals. These results suggest that the ore minerals may be useful as the protectant for allergic and oxidative cell damages.

목차
Abstract
 1. 서 론
 2. 재료 및 방법
  2.1. 실험재료
  2.2. 실험방법
 3. 결 과
  3.1. 광물성 미네랄이 세포 생존율에 미치는 효과
  3.2. 광물성 미네랄이 알레르기성 세포 손상에미치는 효과
  3.3. 광물성 미네랄이 산화적 세포손상에 미치는 효과
  3.4. 광물성 미네랄의 광용혈 억제 효과 측정
 4. 고찰 및 결론
 참 고 문 헌
저자
  • 전유미(순천향대학교 의료생명공학과) | Yu-Mi Jeon (Department of medical biotechnology, SoonChunHyang University)
  • 김점지(순천향대학교 의료생명공학과) | Jum-Ji Kim (Department of medical biotechnology, SoonChunHyang University)
  • 이미영(순천향대학교 의료생명공학과) | Mi-Young Lee (Department of medical biotechnology, SoonChunHyang University) Corresponding Author