Statistical analysis between operating parameters and effluent quality on advanced wastewater treatment plant was performed. Through factor analysis four factors derived varimax rotation were selected each plant. Four components explained 80%, 82% of the total variance of the process, respectively. The components on MLE plant were identified in the following order:1) HRT increase and BOD load decrease by influent decrease, 2) Biomass, 3) SVI increase by internal return increase, 4) Microbial diversity by SRT increase. On A2O plant, we defined them as follows: factor 1, high MLSS by return rate increase, HRT increase by influent decrease; factor 2, biomass; factor 3, BOD of influent; factor 4 was relate to DO.