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Characterization of venom evolution via venom component phylogenetic analysis in Aculeata Hymenoptera

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/364051
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한국응용곤충학회 (Korean Society Of Applied Entomology)
초록

To identify the venom components and their expression patterns of some Aculeata bees/wasps, venom gland-specific transcriptome analysis was conducted. FPKM values were normalized with the average of the transcription level of reference gene (a-tubulin). Common components in both solitary and social wasp venoms include hyaluronidase, phospholipase A2, metalloendopeptidase, etc. Although it has been expected that more diverse bioactive components with the functions of prey inactivation and physiology manipulation are present in solitary wasps, the information on venom compositions of solitary wasps obtained in this study was not sufficient to generalizae this notion. Nevertheless, some neurotoxic peptides (e.g., pompilidotoxin and dendrotoxin-like peptide) and proteins (e.g., insuline-like peptide binding protein) appear to be specific to solitary wasp venom. In contrast, several proteins, such as venom allergen 5 protein, venom acid phosphatase, and various phospholipases, appear to be relatively more abundant in social wasp venom. In the venom gland trancsriptome of bumblebees, major allergens or pain producing factors were barely identified, implying that bumblebee venoms are relatively less toxic than those of social or solitary wasps.

저자
  • Kyungjae Andrew Yoon(Department of Agricultural Biology, Seoul National University)
  • Do Eun Lee(Department of Agricultural Biology, Seoul National University)
  • Woo Young Bang(National Institute of Biological Resources (NIBR), Environmental Research Complex)
  • Chang Hwan Bae(National Institute of Biological Resources (NIBR), Environmental Research Complex)
  • Joo-Hong Yeo(National Institute of Biological Resources (NIBR), Environmental Research Complex)
  • Young Ho Koh(Ilsong Institute of Life Science, Hallym University, Department of Biomedical Gerontology, Hallym University)
  • Si Hyeock Lee(Department of Agricultural Biology, Seoul National University, Research Institute of Agriculture and Life Sciences, Seoul National University)