Virus-like particles (VLPs) are similar to pathogenic viruses, but because they have no nucleic acid, they have excellent safety and immunogenicity and are used as a good vaccine material. However, in the selection of various structural proteins of pathogenic viruses to form VLPs, all expression systems consume a lot of time in common. Among them, the baculovirus expression system causes additional time consumption to construct the recombinant baculovirus. Therefore, there is a need for a system that can rapidly determine the structural proteins required for effective VLP production. This study aims at solving this problem by constructing a BmNPV inducible expression platform through the construction of vectors induced by BmNPV. The platform was evaluated for overexpression using EGFP. We also confirmed the formation of virus-like particles through overexpression of canine parvovirus structural proteins.

• Won Seok Gwak(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)
• Hyun Soo Kim(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)
• Jun Su Bae(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)
• Tae Hee Kim(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)
• Jin Yong Lee(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)
• Soo Dong Woo(Department of agricultural biology, College of Agriculture, Lifr & Environment Science, Chungbuk National University)