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Study on the indoor exposure factors of phthalates using bio-monitoring data

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실내환경 및 냄새 학회지 (Journal of Odor and Indoor Environment)
한국냄새환경학회 (Korean Society Of Odor Research And Engineering)
초록

Phthalate is an endocrine disruptor that interferes with homeostasis and developmental regulation. It is highly toxic to the environment and is associated with various diseases of the human body. Using biological samples from 140 adult subjects, to evaluate the influencing factors which are related to contaminant concentration levels, we used correlation analysis and multiple regression analysis. Lastly, in order to analyze the health effects related to exposure to phthalates, we conducted a risk assessment by estimating acceptable daily intake exposure according to the influential factors. When we compared the concentration level according to influential factors, in general, the subjects who had engaged in home remodeling work had higher urinary phthalate metabolite concentrations levels than the subjects who had not engaged in home remodeling work. We can confirm statistically significant differences in DBP metabolites. In addition, we can confirm the concentration appeared higher in the categories such as using air freshener, sofa and foods. Through conducting a risk assessment of DEHP, BBzP, DiBP, and DnBP by using data on phthalate metabolite concentration in urine, it was found that the average concentration of all metabolites did not exceed TDI.

목차
Abstract
 1. 서 론
 2. 실험방법
  2.1 연구대상자
  2.2 연구 대상항목
  2.3 설문조사
  2.4 프탈레이트 대사체 분석 및 통계분석
  2.5 위해성평가
 3. 실험 결과 및 고찰
  3.1 대상자의 생체 시료 농도
  3.2 영향요인별 농도비교
  3.3 상관성 분석
  3.4 위해성평가
 4. 결 론
 References
저자
  • 양지연(연세대학교 의과대학 환경공해연구소) | Ji Yeon Yang (Institute for Environmental Research, Yonsei University College of Medicine)
  • 신동천(연세대학교 의과대학 예방의학교실) | Dong Chun Shin (Preventive medicine department, Yonsei university college of medicine)
  • 이시은(연세대학교 의과대학 환경공해연구소) | Si Eun Lee (Institute for Environmental Research, Yonsei University College of Medicine)
  • 이건우(연세대학교 의과대학 환경공해연구소) | Geon Woo Lee (Institute for Environmental Research, Yonsei University College of Medicine)
  • 김준혁(연세대학교 의과대학 환경공해연구소) | Joon Hyeog Kim (Institute for Environmental Research, Yonsei University College of Medicine)
  • 이용진(연세대학교 의과대학 환경공해연구소) | Yong Jin Lee (Institute for Environmental Research, Yonsei University College of Medicine)
  • 임영욱(연세대학교 의과대학 환경공해연구소) | Young Wook Lim (Institute for Environmental Research, Yonsei University College of Medicine) Corresponding author