The objective of this study was to investigate the effects of the feeding Cordyceps militaris extract on the improvement of the free fatty acid, lipid peroxide, creatinine and enzyme (creatine phosphokinase; CPK, lactate dehydrogenase; LDH, alkaline phosphatase; ALP, lecithin cholesterol acyltransferase; LCAT) activities in the sera of dietary hypercholesterolemic rats (SD strain, male) fed the experimental diets for 5 weeks. Concentrations of free fatty acid, lipid peroxide and CPK, LDH, ALP activities in sera were fairly reduced in the Cordyceps militaris extract administration group (CHE) than in the hypercholesterolemic diet group (CHD). However, no significance was found in the effect of an creatinine concentration among the groups. The LCAT activity in serum was increased in the Cordyceps militaris extract administration (CHE) than in the hypercholesterolemic diet group (CHD). From these results, Cordyceps militaris extracts were effective on the improvement of the lipid components and metabolic enzyme activities in sera of dietary hypercholesterolemic rats.

Abstract
 1. 서 론
 2. 재료 및 방법
  2.1. 시료의 조제
  2.2. 실험동물의 식이 조성 및 처리
  2.3. 유리지방산 및 과산화지질, creatinine 농도의 측정
  2.4. 효소 활성의 측정
  2.5. 통계처리
 3. 결과 및 고찰
  3.1. 유리 지방산 농도
  3.2. 과산화지질 농도
  3.3. Creatinine 농도
  3.4. 효소 활성의 변동
 4. 결 론
 참 고 문 헌

• 김한수(부산대학교 식품공학과) | Han-Soo Kim (Department of Food Science & Technology, Pusan National University)
• 김민아(부산대학교 식품공학과) | Min-A Kim (Department of Food Science & Technology, Pusan National University)
• 장성호(부산대학교 바이오환경에너지학과) | Seong-Ho Jang (Department of Bioenviromental Energy, Pusan National University) Corresponding author
• 강진순(한국국제대학교 식품과학부) | Jin-Soon Kang (School of Food Science, International University of Korea)
• 이원기(부경대학교 고분자공학과) | Won-Ki Lee (Department of Polymer Engineering, Pukyung National University)
• 류재용(한국원자력연구원 공업환경연구부) | Jae-Young Ryu (Division for Industrial & Environmental Research, Korea Atomic Energy Research Institute (KAERI))