The effects of aloe on the MDA(malondialdehyde) and the blood biochemical components of heavy metal poisoning in SD rat were examined and the following results were obtained. In rat liver homogenate intoxicated with CdCl_2, lipidperoxide was increased each 2.37times(24h), 3.31times(72h) but lipidperoxide in aloe administration groups was lower each 47%, 64% than in heavy metal group. In rat kidney homogenate intoxicated with CdCl_2, lipidperoxide was increased 1.85times(24h), 1.33times(72h) but lipidperoxide in aloe administration groups was almost the same as that of normal group. Lipidperoxide of kidney homogenate was slightly decreased as time passed. Also heavy metal poisoning rats showed high levels(1.38-2.50times) of serum AST, ALT and BUN. However, the administration of aloe significantly inhibited the reduction of them. These results suggest that Cd-induced hepatic and renal injury, via increase lipidperoxide and release of AST, ALT and BUN. Aloe may be used to inhibit or prevent the hepatic and renal toxicity which results from the heavy metal.

• 하배진(신라대학교 화학과) | Bae-Jin Ha (Dept. of Chemistry, Shinla Universily)