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유기인계 및 Carbamates 농약에 의한 Acetylcholinesterase 활성의 저해 KCI 등재

Inhibition of Acetylcholinesterase Activity on the Organophosphorus and Carbamate Pesticides

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한국환경과학회지 (Journal of Environmental Science International)
한국환경과학회 (The Korean Environmental Sciences Society)
초록

The effects of organophosphorus and carbamate pesticides were examined inhibition of the acetylcholinesterase activity in the chicken brain with enzyme - inhibition methods. The acetylcholinesterase activity in chicken brain determined by the Ellman method was 167 μmol/min/g protein. The optimum pH of acetycholinesterase was 8.2. pI_50 of acetycholinesterase by some organophosphorus were 3.80M of phosphorodithioate, 4.04M of phosphorothioate, 6.33M of phosphate, and 6.60M of phosphrothiolate. pI_50 of acetycholinesterase by some carbamates were 5.10M of XMC, 5. 90M of carbofuran, 6.16M of isoprocarb, 6.30M of carbaryl, 6.47M of BPMC, and 6.77M of propoxur. pI_50 of carbamates selected was similar to that of phosphorothioate and phosphate organophosphates

저자
  • 김정호(경산대학교 환경학부) | Jung-Ho Kim (Faculty of Environmental Science and Engineering, Kyungsan University)
  • 김영호(혜전전문대학 호텔제과제빵과) | Young-Ho Kim (Dept. of Hotel Baking Science and Technology, Hyejeon Junior College,)