The objective of this study was to evaluate novel usability as natural anti-obesity supplement of Selaginella tamariscina extract. The total phenol contents and total flavonoid contents were 60.29±3.11 GAE mg/g and 14.90±0.34 QE mg/g, respectively. To evaluate anti-obesity activity of Selaginella tamariscina extract, pancreatic lipase inhibition activity as well as its inhibition effect of lipid accumulation in adipocytes were conducted by Oil Red O staining and lipolysis assay. The result of pancreatic lipase inhibition activity of S. tamariscina extract showed a wide range between 40 and 73% dose dependently. While the incubation of 3T3-L1 cells with S. tamariscina extract inhibited differentiation of preadipocytes and reduced lipid accumulation, the level of released free glycerol into culturing medium was increased in multiple concentrations. These results showed that S. tamariscina extract inhibit adipogenesis and pancreatic lipase activity. Thus, S. tamariscina extract can be a candidate for regulating lipid accumulation in obesity.

Abstract
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 재료 및 방법
 결과 및 고찰
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 References

• 김건희(덕성여자대학교 식물자원연구소) | Gun-Hee Kim (Plant Resources Research Institute, Duksung Women's University) Corresponding author
• 이신영(덕성여자대학교 식물자원연구소) | Shin-Young Lee (Plant Resources Research Institute, Duksung Women’s University)
• 이애랑(숭의여자대학교 식품영양과) | Ae-Rang Lee (Dept. of Food and Nutrition, SoongEui Women’s College)