In the precedent study, the retractable-roof spatial structure was selected as the analytical model and a tuned mass damper (TMD) was installed to control the dynamic response for the earthquake loads. Also, it is analyzed that the installation location of TMD in the analytical model and the optimal number of installations. A single TMD mass installed in the analytical model was set up 1% of the mass of the whole structure, and the optimum installation location was derived according to the number of change. As a result, it was verified that most effective to install eight TMDs regardless of opening or closing. Thus, in this study, eight TMDs were installed in the retractable-roof spatial structure and the optimum mass ratio was inquired while reducing a single TMD. In addition, the optimum mass distribution ratio was identified by redistributing the TMD masses differently depending on the installation position, using the mass ratio of vibration control being the most effective for seismic load. From the analysis results, as it is possible to confirm the optimum mass distribution ratio according to the optimum mass ratio and installation location of the TMD in the the retractable-roof spatial structure, it can be used as a reference in the TMD design for large space structure.