Minute pirate bug, Orius minutus (L.), is a native predator of many small insects such as aphid, scale, thrips, and mites in Korea. Seven chemical pesticides with lower ecotoxicity being used to control those pests were evaluated for acute toxicity against adult female O. minutus in glass scintillation vial assay. In the 1st batch experiment with three pesticides, flonicamid and buprofezin were least toxic whereas in the 2nd batch experiment with four pesticides spirotetramat and spiromesifen showed least toxicity. The corrected mortality of buprofezin and flonicamid became 100% on 55 and 47 h of exposure in 1st batch and that of spirotetramat and spiromesifen became 100% on 75 and 71 h of exposure in 2nd batch, respectively. In conclusion, flonicamid, buprofezin, spirotetramat, and spiromesifen was least toxic among the seven pesticides tested against adult female of O. minutus.