논문 상세보기
pp.475-483
The purpose this study was to investigate the influences of 5% turmeric (Curcuma longa L.) supplementation on enzyme activities such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), amylase, lipase and catalase in serum of dyslipidemic rats. Sprague-Dawley (SD) rats (24 male) were divided into four groups, namely the ND group (normal-nondyslipidemic diet), NT group (normal-nondyslipidemic diet+5% turmeric), DD group (control-dyslipidemic diet), and DT groups (dyslipidemic diet+5% turmeric). Serum concentrations of blood urea nitrogen (BUN), creatinine and uric acid were significantly decreased (p<0.05) by turmeric supplementation diet. The activities of AST, ALT, ALP, LDH, amylase and lipase in sera of turmeric diet group were significantly decreased (p<0.05). The catalase activity in serum of turmeric supplementation group was significantly increased than dyslipidemic diet (p<0.05). In vivo experiment with dyslipidemic rats showed that ingestion of turmeric were effective in kidney and hepatic functional enzyme activities. Which suggests that turmeric material could be used for further studies as a potential source for nutraceutical foods.
1. 서 론
2. 재료 및 방법
2.1. 실험 재료
2.2. 실험 동물
2.3. 식이조성 및 실험군
2.4. 실험 동물의 처치
2.5. 혈액요소질소(BUN), creatinine 및 요산 농도 측정
2.6. 혈청의 효소활성 측정
2.7. 통계 처리
3. 결과 및 고찰
3.1. 혈액요소질소(BUN) 농도
3.2. Creatinine 농도
3.3. 요산(uric acid) 농도
3.4. Aminotransferase (AST, ALT) 활성
3.5. Alkaline phosphatase (ALP) 활성
3.6. Lactate dehydrogenase (LDH) 활성
3.7. 아밀라아제 및 리파아제 활성
3.8. 카탈라아제 활성
4. 결 론
REFERENCES
