Several water tanks installed in the building were damaged during the Gyeongju earthquake (2016) and the Pohang earthquake (2017). Since a water tank for fire protection is very important component, seismic safety should be ensured. In this study, an interaction between a water tank and a building was studied by the dynamic analysis of the RC building with the water tank. In case the water tank was installed on the roof of the RC building, it was confirmed that it did not significantly affect the response of the building. Based on the result, dynamic response characteristics of the water tank in the building were studied using two SDOF models represented dynamic behavior of the water tanks under earthquake. An earthquake time-history analysis was carried out with variables of aspect ratio of the tank, story of the building, and installed location in the building using three kinds of earthquakes.