The masses of supermassive black holes in active galactic nuclei (AGN) can be derived spec- troscopically via virial mass estimators based on selected broad optical/ultraviolet emission lines. These estimates commonly use the line width as a proxy for the gas speed and the monochromatic continuum luminosity, λLλ, as a proxy for the radius of the broad line region. However, if the size of the broad line region scales with the bolometric AGN luminosity rather than λLλ, mass estimates based on different emission lines will show a systematic discrepancy which is a function of the color of the AGN continuum. This has actually been observed in mass estimates based on Hα/Hβ and Civ lines, indicating that AGN broad line regions indeed scale with bolometric luminosity. Given that this effect seems to have been overlooked as yet, currently used single-epoch mass estimates are likely to be biased.