Acute disseminated encephalomyelitis (ADEM) is a rare, postinfectious autoimmune inflammatory demyelinating disease of the central nervous system. ADEM presents clinically encephalopathy in association with polyfocal neurologic deficits. Of them, optic neuritis is less common symptom. We experienced ADEM with optic neuritis associated with Mycoplasma pneumoniae infection in a 5 year-old girl. She initially presented lethargy, irritability, ataxia and loss of pain sense on right hand and progressed to decreased visual acuity and papilledema of both eyes on the 4th hospital day. Brain magnetic resonance imaging showed multiple bilateral hyperintense lesions in the subcortical white matter on T2 weighted images. After administration of intravenous immunoglobulin and high dose intravenous methylprednisolone, she recovered completely.

• 정선진(광주기독병원 소아청소년과) | Seon Jin Jeong (Department of Pediatrics, Kwangju Christian Hospital)
• 김용욱(광주기독병원 소아청소년과) | Yong Wook Kim (Department of Pediatrics, Kwangju Christian Hospital)
• 김경심(광주기독병원 소아청소년과) | Kyoung Sim Kim (Department of Pediatrics, Kwangju Christian Hospital)
• 조형민(광주기독병원 소아청소년과) | Hyoung Min Cho (Department of Pediatrics, Kwangju Christian Hospital)
• 김령(광주기독병원 소아청소년과) | Young Kim (Department of Pediatrics, Kwangju Christian Hospital)
• 장해인(광주기독병원 소아청소년과) | Hae In Jang (Department of Pediatrics, Kwangju Christian Hospital)
• 김은영(광주기독병원 소아청소년과) | Eun Young Kim (Department of Pediatrics, Kwangju Christian Hospital) Corresponding author