We investigate dynamical evolution of globular clusters with multi-mass component under the Galactic tidal field. We compare the results with our previous work which considered the cases of single-mass component m the globular clusters. We find the followings: 1) The general evolutions are similar to the cases of single-mass component. 2) There is no evidence for dependence on the orbital phase of the cluster as in the case of single-mass component. 3) The escape rate in multi-mass models is larger than that in the single-mass models. 4) The mass-function depends on radius more sensitively in anisotropic models than in isotropic models.