Vortex tube is a simple structure and environmentally friendly method of temperature separation. In this paper, the applicability of the vehicle air conditioning system using the Vortex tube was reviewed. Experimental conditions, the pressure was set at 0.5~5.0kgf/cm2, and the cold air flow ratio (yc) was set at 0.1~0.9. Experiment result, the high temperature section represents the highest temperature value at yc=0.8. The cold zone represents the lowest temperature value at yc=0.5. In case of indirect heat exchanger experiment result, the maximum temperature difference was 11°C in the cold zone and 15°C in the hot zone. In case of direct heat exchange, the low temperature area was 11°C and the high temperature area was 11°C. According to the experiment result, although indirect heat exchange method performs better than direct heat exchange method, the time to reach normal temperature is four times slower than direct heat exchange method. Therefore, in order to apply to a vehicle air conditioning system, it is judged that it is effective to use a direct heat exchange method having a fast reaction speed and a low flow rate resistance.