The development of drugs from natural plant sources is at growing interest due to the limitations of chemical drugs in terms of side effects and cost-effective factors of natural medicines. Among the various components contained in natural plant materials, flavonoids are of increasing interest because of their extended biological benefits. Flavonoids are classified into various types according to their structure and possess different activities depending on the structure. In this study, the flavonoids contained in Artemisia, native to Korea were examined and reviewed. HPLC chromatograms of three Artemisia species (Artemisia annua L., Artemisia iwayomogi and Artemisia argyi H.) were examined from published sources and their component analysis by MS data were summarized. The various flavonoids of Artemisia were classified into 12 types according to the main structure, and 10 flavonoids based on various activities were examined. The 10 flavonoids were identified as quercetin, kaempferol, rhamnetin, diosmetin, luteolin, methoxyflavone, catechin, apigenin, malvidin and genkwanin with extensive reported studies till date. The ten flavonoids examined have been reported to be effective in preventing and treating various diseases and exhibit activities such as anti-cancer, anti-inflammatory, antioxidant, antiviral, anti-obesity, anti-diabetic and anti-Alzheimer. The collective results from the reported studies suggest that the three types of Korean native Artemisia, contains various flavonoids with beneficial activities and may have therapeutic effects against diseases.

Introduction
    Chromatogram of flavonoids and components containedin Artemisia
    Components present in Artemisia annua L. and itsreported functions
    Components present in Artemisia iwayomogi andits reported functions
    Components present in Artemisia argyi H. and itsreported functions
    Functions of 10 identified flavonoids in the threespecies of Artemisia family
Conclusion
References

• Hun Hwan Kim(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University)
• Preethi Vetrivel(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University)
• Sang Eun Ha(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University)
• Pritam Bhagwan Bhosale(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University)
• Ho Jeong Lee(Biological Resources Research Group, Gyeongnam Department of Environment Toxicology and Chemistry, Korea Institute of Toxicology (KIT))
• Jin-A Kim(Department of Physical Therapy, International University of Korea)
• Kwang Il Park(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University)
• Seong Min Kim(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University) Corresponding author
• Gon Sup Kim(Research Institute of Life Science and College of Veterinary Medicine, Gyeongsang National University) Corresponding author