Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects of Brassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal control group was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After 4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcohol concentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in rat model. Furthermore, BOE increased detoxificative abilities against alcohol.

Abstract
Introduction
Materials and Methods
    Preparation of BOE
    Reagents and kits
    Animal model
    Histologic experiments
    Statistical analysis:
Results and Discussion
References

• Min Jeong Kim(Korea Food Research Institute)
• Hye Jeong Yang(Korea Food Research Institute)
• Hak Yong Lee(INVIVO Co. Ltd.)
• Young Mi Park(INVIVO Co. Ltd.)
• Dong Yeop Shin(INVIVO Co. Ltd.)
• Yang Hee Lee(INVIVO Co. Ltd.)
• Yang Gyu Kang(INVIVO Co. Ltd.)
• Tae Su Kim(Anydoctor HealthCare Co. Ltd.)
• Sung Pyo Lee(Anydoctor HealthCare Co. Ltd.)
• Kwang-Hyun Park(Department of Emergency Medical Rescue and Department of Oriental Pharmaceuticals Development, Nambu University/Department of Emergency Medicine, Graduate School of Chonnam National University) Corresponding author