내구성을 포함한 친수성 실리콘 콘택트렌즈의 물리적 특성
목적 : 본 연구는 실리콘과 친수성 단량체를 포함하는 기능성 실리콘 콘택트렌즈를 제조하기 위해 Isobornyl Methacrylate 및 2-(Trifluoromethyl)styrene을 사용하여 물리적, 광학적 특성을 분석하였다.
방법 : 고분자의 중합은 실리콘 모노머와 친수성 단량체인 DMA(N,N-Dimethylacrylamide), 가교제인 EGDMA (Ethylene glycol dimethacrylate) 그리고 개시제인 AIBN(azobisisobutyronitrile)을 사용하여 공중합하였다. 첨 가제는 Isobornyl Methacrylate와 2-(Trifluoromethyl)styrene를 각각 사용하였으며, 제조된 콘택트렌즈의 물 성 변화를 알아보기 위해 분광투과율, 굴절률, 산소투과율, 인장강도 등을 측정하였다.
결과 : 제조된 친수성 콘택트렌즈의 산소투과율은 실리콘의 영향으로 33.22×10-11(cm2/s)(mlO2/ml×mmHg) 으로 나타났다. 첨가제인 Isobornyl Methacrylate의 양이 증가함에 따라 굴절률은 다소 향상되었고, 분광투과율은 첨 가제 양에 따라 가시광선 영역에서 약 15% 향상되어 투명한 콘택트렌즈가 제조되었다. 또한 2-(Trifluoromethyl) styrene의 첨가량에 따라 인장강도는 약 45% 향상된 것으로 나타났다.
결론 : 본 연구를 통해 제조된 실리콘 콘택트렌즈는 콘택트렌즈의 기본적인 물성을 만족시키면서 고산소투과성 을 가지며, Isobornyl Methacrylate 및 2-(Trifluoromethyl)styrene는 각각 상용성과 내구성을 향상시키는 것 으로 나타나 콘택트렌즈 재료로 다양하게 활용될 수 있을 것으로 판단된다.
Purpose : The optical characteristics of isobornyl methacrylate and 2-(trifluoromethyl)styrene were analyzed to produce a functional silicone contact lens containing silicone and hydrophilic monomer.
Methods : Silicone was produced by copolymerizing a silicone monomer, with N,N-dimethylacrylamide (DMA), a hydrophilic monomer, ethylene glycol dimethacrylate (EGDMA), a cross-linking agent, and azobisisobutyronitrile (AIBN), an initiator. For additives, isobornyl methacrylate and 2- (trifluoromethyl)styrene were used separately. To examine the changes in physical properties of the fabricated contact lens, spectral transmittance, refractive index, oxygen permeability, and tensile strength were measured.
Results : The oxygen permeability of the produced hydrophilic contact lens was 33.22×10-11 (cm2/s)(mlO2/ml×mmHg) due to the effect of silicone. As the amount of the additive, isobornyl methacrylate increased, the refractive index improved somewhat and the spectral transmittance in the visible spectrum improved by approximately 15%, producing a transparent contact lens. Furthermore, the tensile strength improved by approximately 45% with the addition of 2- (trifluoromethyl)styrene.
Conclusion : It was confirmed that the silicone contact lens fabricated in this study satisfies the basic physical properties of the contact lens and has high oxygen permeability. It was also confirmed that the compatibility was improved by adding isobornyl methacrylate, and the durability was improved by adding 2-(trifluoromethyl)styrene. Therefore, it is considered that the two additive materials can be used in various ways as a contact lens material according to the improved compatibility and durability of the silicone contact lens.