Prognosis of unresectable pancreatic cancer is poor with the rate of surviving more than 5 years is less than 10% despite multi-modalities treatment. The American Society of Clinical Oncology suggested that all patients with metastatic pancreatic cancer should be offered information about clinical trials. Endoscopic ultrasound guided radio frequency ablation has been recently used in patients with advanced stage pancreatic cancer in a few studies. This article has reviewed information from published articles using endoscopic ultrasound guided radio frequency ablation for advanced pancreatic cancer.

INTRODUCTION
MAIN BODY
    1. Tools
    2. Operation procedures at the King ChulalongkornMemorial Hospital (KCMH)
    3. Efficacy of EUS-RFA for pancreatic cancer(Table 1)
    4. Relieving abdominal pain from pancreaticcancer
    5. Indications and contraindications
CONCLUSIONS
REFERENCES

• Pradermchai Kongkam(Gastrointestinal Endoscopy Excellence Center and Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital)
• Rungsun Rerknimitr(Gastrointestinal Endoscopy Excellence Center and Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital) Corresponding author