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pp.278-285
This study produces electroconductive polycaprolactone (PCL)-based film with different amounts of graphene (G) through electrospinning, and the characteristics of the produced G/PCL composites are investigated. The G/PCL results are analyzed by comparing them with those obtained using pure PCL electrospun film as a control. The morphology of electrospun material is analyzed through scanning electron microscopy and transmission electron microscopy. Mechanical and electrical properties are also evaluated. Composites containing 1% graphene have the highest elongation rate, and 5% samples have the highest strength and elasticity. Graphene contents > 25% show electro-conductivity, which level improves with increase of graphene content. Biological characteristics of G/PCL composites are assessed through behavioral analysis of neural cell attachment and proliferation. Cell experiments reveal that compositions < 50% show slightly reduced cell viability. Moreover, graphene combinations facilitated cell proliferation compared to pure PCL. These results confirm that a 25 % G/PCL composition is best for application to systems that introduce external stimuli such as electric fields and electrodes to lead to synergistic efficiency of tissue regeneration.
1. 서 론
2. 실험 방법
2.1 재료 준비
2.2 전기방사 실험
2.3 전기방사 섬유형 필름의 특성 분석
2.4 전기저항성 측정
2.5 세포 부착 및 증식
3. 결과 및 고찰
3.1 G/PCL 복합체 전기방사 섬유형 필름의 제조
3.2 기계적 특성
3.3 복합체의 전기적 특성
3.4 세포거동 분석
4. 결 론
References
