The spatial variation characteristics of seismic motions at the nuclear power plant's site and structures were analyzed using earthquake records obtained at the Fukushima nuclear power plant during the Great East Japan Earthquake. The ground responses amplified as they approached the soil surface from the lower rock surface, and the amplification occurred intensively at about 50 m near the ground. Due to the soil layer's nonlinear characteristics caused by the strong seismic motion, the ground's natural frequency derived from the response spectrum ratio appeared to be smaller than that calculated from the shear wave velocity profile. The spatial variation of the peak ground acceleration at the ground surface of the power plant site showed a significant difference of about 0.6 g at the maximum. As a result of comparing the response spectrums at the basement of the structure with the design response spectrum, there was a large variability by each power plant unit. The difference was more significant in the Fukushima Daiichi site record, which showed larger peak ground acceleration at the surface. The earthquake motions input to the basement of the structure amplified according to the structure's height. The natural frequency obtained from the recorded results was lower than that indicated in the previous research. Also, the floor response spectrum change according to the location at the same height was investigated. The vertical response on the foundation surface showed a significant difference in spectral acceleration depending on the location. The amplified response in the structure showed a different variability depending on the type of structure and the target frequency.