Gray mold is caused by the fungal pathogen Botrytis cinerea (B. cinerea), a commercially damaging disease of rose flowers. The infection of this necrotrophic fungal pathogen is one of the most important reason that rose flower is rejected by consumers and importers, leading to economic losses. The gray mold disease influences rose flowers through cultivation and distribution in the greenhouse, storage, transport, and market. Environmental conditions and genetic factors are two primary factors that affect the development of gray mold in the flowers during pre- and postharvest stages. However, the interaction between B. cinerea and rose flowers at the molecular level has not been well studied to date. Despite the multiple studies conducted over the past decades, breeding flowers that have resistance to B. cinerea has not been successful in roses. Furthermore, the mechanism underlying tolerance to gray mold is under-investigated and poorly understood in roses. The most popular current control strategies against B. cinerea in roses are pre- and postharvest fungicides, but they are generally expensive, ineffective, and polluted. In this review, we summarized the nature of B. cinerea in plants and discussed the current control strategies of gray mold disease in rose flowers, such as radiation, resistance inducer, chemical and biological control. In addition, we propose an approach for reducing B. cinerea infection in rose flowers by using ethylene antagonists.

Abstract
Introduction
Botrytis cinerea Pathosystem in Rose Flowers
    Control Strategies of B. cinerea in Rose Flowers
    Chemical Control
    Radiation Control
    Biological Control
    Resistance Inducer
    Control B. cinerea in Rose Flowers by EthyleneInhibitors
Conclusion
References

• Suong Tuyet Thi Ha(Division of Horticulture and Medicinal Plant, Andong National University)
• Bongsu Choi(Plant Resources Division, National Institute of Biological Resources)
• Byung-Chun In(Division of Horticulture and Medicinal Plant, Andong National University) Corresponding author