The abnormal meat could caused by abscess, fibrosis and granuloma in the region of the neck by the adverse effect of foot-and-mouth disease (FMD) vaccination practice for Korean swine. After FMD vaccination was implemented in 2010, the number of incidences of abnormal meat has been increasing. In this study, it was evaluated whether needless intradermal injection (NII) of FMD vaccine reduces abnormal meat at the injection site in comparison to conventional intramuscular injection (IM). In addition, the onset of humoral immunity was analyzed in order to see if NII of this vaccine is able to mount comparable antibody response with IM. This study was carried out in four Korean pig farms. The O-type FMD vaccine was implemented via NII at three farms and the control group was vaccinated via IM. Antibody titers were compared from the serum samples taken from 10 random pigs at age of 8, 12, 16 and 22~24 weeks of age. The O+A type FMD vaccine was also compared with the same protocol. When test animals were slaughtered, incidence, type and size of abnormal meat were recorded. The results of this study showed that the antibody titers between intradermal and intramuscular group were similar but a significant difference in the incidence of abnormal meat formation was observed between two groups (p < 0.05). In summary, needless intradermal injection of FMD vaccination was proven to be effective for the onset of humoral immunity and reducing abnormal meat formation.

Abstract
서 론
재료 및 방법
    구제역백신
    공시돈
    백신접종
    SP항체가 비교
    접종부위 이상육 검사
    통계분석
결 과
    SP항체 양성율 비교
    이상육 발생율
    이상육 종류
    이상육 크기
고 찰
결 론
REFERENCES

• Chang-Won Im(Laboratory of Veterinary Bacteriology, College of Veterinary Medicine, Chungbuk National University/Dodram Pig Farmer’s Cooperative, Pig Special Hospital)
• Wan-Kyu Lee(Laboratory of Veterinary Bacteriology, College of Veterinary Medicine, Chungbuk National University) Corresponding Author