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The Analysis of COVID-19 Pooled-Testing Systems with False Negatives Using a Queueing Model KCI 등재

대기행렬을 이용한 위음성률이 있는 코로나 취합검사 시스템의 분석

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한국산업경영시스템학회지 (Journal of Society of Korea Industrial and Systems Engineering)
한국산업경영시스템학회 (Society of Korea Industrial and Systems Engineering)
초록

COVID-19 has been spreading all around the world, and threatening global health. In this situation, identifying and isolating infected individuals rapidly has been one of the most important measures to contain the epidemic. However, the standard diagnosis procedure with RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) is costly and time-consuming. For this reason, pooled testing for COVID-19 has been proposed from the early stage of the COVID-19 pandemic to reduce the cost and time of identifying the COVID-19 infection. For pooled testing, how many samples are tested in group is the most significant factor to the performance of the test system. When the arrivals of test requirements and the test time are stochastic, batch-service queueing models have been utilized for the analysis of pooled-testing systems. However, most of them do not consider the false-negative test results of pooled testing in their performance analysis. For the COVID-19 RT-PCR test, there is a small but certain possibility of false-negative test results, and the group-test size affects not only the time and cost of pooled testing, but also the false-negative rate of pooled testing, which is a significant concern to public health authorities. In this study, we analyze the performance of COVID-19 pooled-testing systems with false-negative test results. To do this, we first formulate the COVID-19 pooled-testing systems with false negatives as a batch-service queuing model, and then obtain the performance measures such as the expected number of test requirements in the system, the expected number of RP-PCR tests for a test sample, the false-negative group-test rate, and the total cost per unit time, using the queueing analysis. We also present a numerical example to demonstrate the applicability of our analysis, and draw a couple of implications for COVID-19 pooled testing.

목차
1. 서 론
2. 코로나 취합검사 시스템의 대기행렬 모형
    2.1 그룹 검사의 민감도
    2.2 취합검사 시간의 분포
    2.3 취합검사 당 검사 횟수의 분포
    2.4 그룹 검사에서 위음성으로 진단되는 양성 검체수의 분포
3. 취합검사 시스템 내의 검체 수 분포
4. 취합검사 시스템의 성능 지표
5. 수치 예제
6. 결 론
References
저자
  • Kilhwan Kim(상명대학교 경영공학과) | 김길환 Corresponding Author