In this study, chemically enhanced steam cleaning(CESC) was applied as a novel and efficient method for the control of organic and inorganic fouling in ceramic membrane filtration. The constant filtration regression model and the resistance in series model(RISM) were used to investigate the membrane fouling mechanisms. For total filtration, the coefficient of determination(R2) with an approximate value of 1 was obtained in the intermediate blocking model which is considered as the dominant contamination mechanism. In addition, most of the coefficient values showed similar values and this means that the complex fouling was formed during the filtration period. In the RISM, Rc/Rf increased about 4.37 times in chemically enhanced steam cleaning compared to physical backwashing, which implies that the internal fouling resistance was converted to cake layer resistance, so that the membrane fouling hardly to be removed by physical backwashing could be efficiently removed by chemically enhanced steam cleaning. The results of flux recovery rate showed that high-temperature steam may loosen the structure of the membrane cake layer due to the increase in diffusivity and solubility of chemicals and finally enhance the cleaning effect. As a consequence, it is expected that chemically enhanced steam cleaning can drastically improve the efficiency of membrane filtration process when the characteristics of the foulant are identified.