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The Making of a Competent Oocyte – A Review of Oocyte Development and Its Regulation KCI 등재

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/414973
  • DOIhttps://doi.org/10.12750/JARB.35.1.2
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한국동물생명공학회지 (구 한국수정란이식학회지) (Journal of Animal Reproduciton and Biotechnology)
한국동물생명공학회(구 한국수정란이식학회) (Journal of Animal Reproduction & Biotechnology)
초록

Assisted reproductive technologies (ART) merely depend on improving the oocyte maturation and their developmental competence to produce good quality embryos. Oocyte maturation passes through long and complex molecular steps starts from the early embryonic life and ends with sperm fertilization. Oocyte developmental competence can be attained by improving the nuclear and cytoplasmic mechanisms together with some epigenetic maturation. In this review, we highlight the cornerstones of oocyte maturation on both nuclear and cytoplasmic levels. Interfering or supporting these molecular mechanisms would help in the development of novel regulating agents for reproductive performance of humans and livestock species.

목차
ABSTRACT
INTRODUCTION
THE OVARY AND FOLLICULOGENESIS
OOCYTE MATURATION, MEIOSIS ANDMEIOTIC ARREST
OOCYTE MEIOTIC RESUMPTION
CYTOPLASMIC MATURATION
OOCYTE CYTOPLASMIC MOLECULARMATURATION
EPIGENETIC MATURATION OF OOCYTES
CONCLUSION
CONFLICTS OF INTEREST
ACKNOWLEDGEMENTS
AUTHOR CONTRIBUTIONS
AUTHOR’S POSITION AND ORCID NO.
REFERENCES
저자
  • Hammed A. Tukur(Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia)
  • Riyadh S. Aljumaah(Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia)
  • Ayman Abdel-Aziz Swelum(Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia, Department of Theriogenology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt)
  • Abdullah N. Alowaimer(Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia)
  • Islam M. Saadeldin(Department of Animal Production, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia, Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt) Corresponding author