Climate change due to global warming causes a rise in atmospheric air temperature to rise and extreme shift in precipitation patterns. Carbon dioxide (CO2) is widely known as one of the major cause of global warming and accounts for about 72% of total greenhouse gas emissions. Agriculture is more vulnerable to climate change than other industries. Many studies have been conducted to investigate how agroecosystems, both natural and controlled, will respond to the rising level of CO2. Studies on the responses of crops and agricultural environments to climate change are crucial in predicting changes in agro-ecosystems. Research facilities for various types of CO2 treatment have been developed. The representative research facilities are SAR (Soil-Plant-Atmosphere-Research), OTC (Open Top Chamber), FACE (Free Air CO2 Enrichment System), and TGC & CTGC (Temperature Gradient Chamber & CO2-Temperature Gradient Chamber). Therefore, this study reviewed research data and their application in agriculture.