The objective of this study is to analyze the difference between the theoretically calculated torque values of lead screws used in vehicle seat rails and the required torque values due to various disturbances that occur in actual systems. Lead screws were classified into square and trapezoidal threads and modeled by two lead type. Dynamic analysis models were constructed by applying contact conditions and rotational joints between the lead screw and nut. The validity of the dynamic model was verified by comparing the torque values obtained from rigid body dynamic analysis with the theoretically calculated torque values. Then, the lead screw was modeled as a flexible body to investigate the torque variation required for the lead screw when dynamic loads are considered. This study will help predict the actual torque values of lead screws for seat rails.