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pp.462-470
The aim of this study was to investigate the hypoglycemic effects of saengshik in Sprague-Dawley (SD) rats and to explore the potential of three commercially available saengshik products (BS, LS, WS) as an alternative diabetic meal. Blood glucose levels were measured at 30, 60, 90, 120, and 150 minutes after the ingestion of experimental materials. In experiment 1, the amount of experimental materials remained the same. We measured blood glucose-related biomarkers as the area under the blood glucose response curve (AUC), glycemic index (GI), maximum concentration (Cmax), and time to reach maximum concentration (Tmax). AUC and Cmax of the experimental group showed significant differences compared to the control group, while GI and Tmax did not show significant differences among the groups but were lower in the experimental group compared to the control group. In experiment 2, carbohydrates were adjusted to the same amount. We measured blood glucose-related biomarkers in the same manner as Experiment 1 and obtained similar results. These hypoglycemic effects appear to be attributed to phytochemicals and dietary fiber found in whole, unrefined grains. These results suggest that saengshik exerts hypoglycemic effects by modulation of glucose-related biomarkers.
재료 및 방법
1. 실험재료 및 시험물질
2. 실험동물의 사육
3. 경구당부하 검사 및 혈당 측정
4. 혈당지수(glycemic index) 평가
5. 통계분석
결과 및 고찰
1. 실험 1: 동일한 양으로 제조한 시료의 혈당 및 혈당관련 지표
2. 실험 2: 탄수화물 함량을 보정한 시료의 혈당 및 혈당관련 지표 평가
요약 및 결론
References
