Background: The potential impact of aqueous extracts from Psidium guajava leaves on the reproductive system of female rabbits was evaluated. Methods: Twenty-eight rabbits, aged five to six months were utilized. Rabbits were divided into four groups and were randomly assigned to receive one of the following oral doses of the guava leaf extracts: 0 (control group), 10, 20, or 30 mg/kg of body weight. After a treatment period of 30 days, blood was collected via jugular venipunture and the serum was extracted for the assessment of serum biochemical traits levels. The females were bred and monitored throughout their pregnancy to ascertain reproductive outcomes. Results: The results indicated that the guava leaf extract significantly increased the body weight of the rabbits during both pre- and post-pregnancy compared to the control group (p < 0.05). The litter size at three weeks post-birth, prolificity rate, FSH, LH, and protein levels were notably higher (p < 0.05) at a dose of 20 mg/kg of body weight. The viability rate three weeks post-birth increased with escalating extract doses, and the highest values were observed at doses of 20 and 30 mg/kg of body weight (p < 0.05). Conclusions: This study demonstrated that, the aqueous extract of guava leaves appears to stimulate the production of FSH, LH and enhance body weight, prolificity, and pregnancy outcomes in mammals. As such, it is suggested that a dose of 20 mg/kg body weight could be beneficial in improving the reproductive performance of female.

INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES

• Azafack Kana Dorice(Animal Physiology and Health Research Unit, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang 222, Cameroon, Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, University of Buea, Buea 63, Cameroon) Corresponding author
• Paguem Eric Achile(Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, University of Buea, Buea 63, Cameroon)
• Deutcheu Nienga Sorelle(Department of Animal Sciences, Faculty of Agriculture and Veterinary Medicine, University of Buea, Buea 63, Cameroon)
• Tchoffo Hervé(Animal Physiology and Health Research Unit, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang 222, Cameroon)
• Chongsi Margaret Momo(Animal Physiology and Health Research Unit, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang 222, Cameroon)
• Ngwafu Nancy Ngwasiri(Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, University of Buea, Buea 63, Cameroon)
• Ferdinand Ngoula(Animal Physiology and Health Research Unit, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang 222, Cameroon)