Around the world, Nuclear Power Plants (NPPs) have been operated since the 1950s and are used as a major power source. In Korea, Kori unit 1 stared commercial operation for the first time in 1978, and as of 2023, 25 units of NPPs are in operation. NPPs produce electricity for about 40 to 60 years after receiving an operating license, and after securing safety through a safety evaluation, the operating period is extended. NPPs that operate for a long time are systematically evaluated for safety at regular intervals through Periodic Safety Review (PSR) recommended by the IAEA. In Korea, PSR has been introduced and performed since 2000. This study reviewed the process of the PSR by comparing with the international PSR procedure. The PSR process is established through the IAEA SSG-25 document and proceeds in the order of establishment of basis document - individual factor evaluation - global assessment - integrated improvement plan. In Korea, PSR is carried out in a similar process, but there are some differences from the IAEA’s procedure. The safety factor review is conducted under the agreement of basis document between the licensee and the regulatory body, but the prior agreement procedure with the regulatory body is not reflected in Korea. As a result, if the licensee and the regulatory body have different opinions on the current licensing basis and the modern safety standards after the evaluation is performed, a difference may occur in the review results and safety enhancement items, which may lead to inefficient PSR progress. PSR is conducted for the continuous safe operation and management of NPPs, and it is important to refer to overseas standards and cases. Although procedures, guidelines, and regulatory requirements are in place in Korea, continuous review and improvement are required. It is necessary to improve procedures such as basis document and global assessment in order to more efficiently carry out PSR evaluation by regulatory agency and licensee’s safety enhancement actions of domestic NPPs