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Hematological characteristics and endocrine profiles of cloned dromedary camels (Camelus dromedaries ) KCI 등재

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한국동물생명공학회지 (구 한국수정란이식학회지) (Journal of Animal Reproduciton and Biotechnology)
한국동물생명공학회(구 한국수정란이식학회) (Journal of Animal Reproduction & Biotechnology)
초록

Background: Somatic cell nuclear transfer (SCNT) is a prominent technology that can preserve superior genetic traits of animals and expand the population in a short time. Hematological characters and endocrine profiles are important elements that demonstrate the stability of the physiological state of cloned animals. To date, several studies regarding cloned camels with superior genes have been conducted. However, detailed hemato-physiological assessments to prove that cloned camels are physiologically normal are limited. In this study, We evaluated the hemato-physiological characteristics of cloned male and female dromedary camels (Camelus dromedaries). Methods: Therefore, we analyzed variations in hematological characteristics and endocrine profiles between cloned and non-cloned age-matched male and female dromedary camels (Camelus dromedaries ). Two groups each of male and female cloned and non-cloned camels were monitored to investigate the differences in hemato-physiological characteristics. Results: All the animals were evaluated by performing complete blood count (CBC), serum chemistry, and endocrinological tests. We found no significant difference between the cloned and non-cloned camels. Furthermore, the blood chemistry and endocrine profiles in male and female camels before maturity were similar. Conclusions: These results suggest that cloned and non-cloned camels have similar hematological characteristics and endocrine parameters.

목차
INTRODUCTION
MATERIALS AND METHODS
    Chemicals
    Animals
    Blood sample collection
    Hematological and endocrinal analysis
    Statistical analysis
RESULTS
    Analysis of hematological values
    Analysis of biochemistry and endocrine profiles
DISCUSSION
CONCLUSION
REFERENCES
저자
  • Young-Bum Son(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates, Department of Obstetrics, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Korea)
  • Mohammad Shamim Hossein(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Yeon Ik Jeong(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Mina Kang(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Huijeong Kim(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Yura Bae(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Kung Ik Hwang(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates)
  • Alex Tinson(Hilli E.T. Cloning and Surgical Centre, Presidential Camels and Camel Racing Affairs, Abu Dhabi 17292, United Arab Emirates)
  • Singh Rajesh(Hilli E.T. Cloning and Surgical Centre, Presidential Camels and Camel Racing Affairs, Abu Dhabi 17292, United Arab Emirates)
  • Al Shamsi Noura(Hilli E.T. Cloning and Surgical Centre, Presidential Camels and Camel Racing Affairs, Abu Dhabi 17292, United Arab Emirates)
  • Woo Suk Hwang(UAE Biotech Research Center, Abu Dhabi 30310, United Arab Emirates, Department of Biology, North-Eastern Federal University, Yakutsk 677000, Russia) Corresponding author