Background: Mobilization with movement (MWM) is an effective intervention for increasing range of motion (ROM) and function without pain. Objectives: The purpose of this study is to comprehensively characterize the functional effects of MWM applied to the ankle joint in patients with stroke. Design: Systematic Review and Meta-analysis. Methods: International electronic databases, CINAHL, Embase, MEDLINE, PubMed, and Google scholar were included and identified after review by two investigators in July 2023 according to PRISMA guidelines. Data were synthesized using software provided by Cochran and analyzed using a random effects model with reweighting to account for heterogeneity between participants. Results: After excluding duplicate studies, 14 of the 19 articles screened through the abstracts were excluded, resulting in a total of five studies involving 109 participants with stroke. MWM showed significant differences in ankle ROM [overall effect (Z=3.27, P=0.00)], gait speed [overall effect (Z=3.33, P=0.00)], and cadence [overall effect (Z=2.49, P=0.01)]. Conclusion: The results of the meta-analysis confirmed that MWM is effective in improving ankle ROM and gait parameters in patients with stroke.

INTRODUCTION
METHODS
    Study design
    Eligibility criteria
    Search strategy
    Data extraction
    Quality assessment
    Strategy for data synthesis
RESULTS
    Literature search and characteristics of the includedrandomized clinical trials
    Methodological quality assessment
    MWM applied to the ankle of a patients with chronicstroke
    Effect of MWM applied to the ankle-on-ankle ROM inpatients with stroke
    Effect of MWM applied to the ankle on the gait abilityof patients with stroke
DISCUSSION
CONCLUSION
FUNDING
REFERENCES

• Shinjun Park(Department of Physical Therapy, Suwon Women’s University, Hwaseong, Republic of Korea) Corresponding author
• Yunghyun Jeon(Department of Physical Therapy, Yongin University, Yongin, Republic of Korea)
• Dajeong Kim(Department of Physical Therapy, GSAM Hospital, Gunpo, Republic of Korea)