Recently, it is demonstrate that the invertebrates have a immune memory, called Immune priming (IP). It was partially studied that the IP is mainly regulated by epigenetic modification. Here, to understand the IP on antimicrobial peptides (AMPs) production, we investigated larval mortality and time-dependent expression patterns of AMP genes in T. molitor larvae challenged with E. coli (two-times injection with a one-month interval). Interestingly, the results indicate that the higher and faster expression levels of most AMP genes were detected compared to the non-primed T. molitor larvae. Our results may used to improve the understanding of mechanisms of invertebrate immune memory.

• Jea Hui Kim(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Ho Am Jang(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Hyeon Jun Shin(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Jun Yang Jeong(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Seo Jin Lee(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Sung Min Ku(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Dong Woo Kang(Department of Biology, College of Natural Sciences, Soonchunhyang University)
• So Yeon Choi(Department of Biology, College of Natural Sciences, Soonchunhyang University)
• Yong Seok Lee(Department of Biology, College of Natural Sciences, Soonchunhyang University, Korea Native Animal Resources Utilization Convergence Research Institute (KNAR), Soonchunhyang University)
• Yeon Soo Han(Department of Applied Biology, College of Agriculture and Life Sciences, Chonnam National University)
• Yong Hun Jo(Department of Biology, College of Natural Sciences, Soonchunhyang University)