목적 : 본 연구에서는 젤라틴 메타크릴레이트(GelMA)를 합성하고 이를 기본 하이드로겔 렌즈 혼합물과 함께 교 반한 후 제조된 렌즈의 물성을 비교 분석하여 고기능성 소재로서의 적용성을 확인하고자 하였다. 방법: 젤라틴 메타크릴레이트(GelMA) 합성에는 젤라틴(A형), 인산완충식염수(Phosphate buffer solution, PBS), methacrylic anhydride(MA)를 사용하였다. 또한, 주재료인 2-hydroxyethyl methacrylate(HEMA)와 광 개시제인 2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone(Irgacure 2959), 교차결합제인 ethylene glycol dimethacrylate(EGDMA)를 각각 사용하였다. 제조된 렌즈의 물성 분석을 위해 광투과도, 굴절률, 함수율, 접촉각을 평가하였다. 결과: GelMA의 합성은 EDS를 통해 확인되었다. 제조된 렌즈의 물성을 측정한 결과, 가시광선 투과도는 91.33~ 71.02%, 굴절률은 1.4383~1.4365, 함수율은 39.08~39.04%, 접촉각은 70.83~70.43°로 나타났으며, GelMA 첨가 비율이 증가할수록 굴절률이 증가하였다. 결론 : GelMA 첨가 시 하이드로겔 렌즈의 함수율과 습윤성에 영향을 미치지 않으면서 굴절률 증가에 효과적이 며 UV-B 및 UV-A 영역을 차단하는 기능을 나타내었다. 따라서 본 연구 결과, GelMA가 첨가된 하이드로겔 소 재는 고굴절률 및 시기능성 렌즈 소재로 다양하게 활용될 수 있을 것으로 판단된다.

Purpose : This study attempted to confirm its applicability as a high-functional material by synthesizing gelatin methacrylate (GelMA) and incorporating it into it with a basic hydrogel lens mixture, and then comparing and analyzing the physical properties of the manufactured lens. Methods : GelMA, phosphate buffer solution (PBS), and methacrylic anhydride (MA) were used for the synthesis of GelMA. In addition, 2-hydroxyethyl methacrylate, which is a main material, and 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone (Irgacure 2959), which is a crosslinking agent, were used, respectively. For the analysis of physical properties of the manufactured lens, optical transmittance, refractive index, watere content, and contact angle were evaluated. Results : The synthesis of GelMA was confirmed through energy dispersive spectroꠓscopy (EDS). As a result of measuring the physical properties of the prepared lens, the visible light transmittance was 91.33 to 71.02% and the refractive index was 1.4383 to 1.4365, the water content was 39.08 to 39.04%, and the contact angle was 70.83 to 70.43°, respectively. As the addition ratio of GelMA increased, the refractive index also increased. Conclusion : The addition of GelMA is effective in increasing the refractive index without affecting the water content and wettability of the hydrogel lens, and has the function of blocking UV-B and UV-A regions. Therefore, this study concludes that the hydrogel material with added GelMA can be utilized in various ways as a material for high refractive index and visibilityfunctional lenses.

Ⅰ. Introduction
Ⅱ. Materials and methods
    1. Reagents and materials
    2. Synthesis and polymerization
    3. Measuring Device and Methods
Ⅲ. Results and Discussion
    1. Analysis of Synthesized of GelMA
    2. Spectral transmittance of samples
    3. Refractive index and water content of samples
    5. Contact angle of samples
Ⅳ. Conclusion
References
요 약

• Chae Young Kim(Dept. of Optometry & Vision Science, Daegu Catholic University, Student, Daegu) | 김채영 (대구가톨릭대학교 안경광학과, 학생, 대구)
• A-Young Sung(Dept. of Optometry & Vision Science, Daegu Catholic University, Professor, Daegu) | 성아영 (대구가톨릭대학교 안경광학과, 교수, 대구) Corresponding author