Herein, facile room-temperature self-assembly and high-temperature pyrolysis strategy was successively conducted for in situ synthesizing novel TiO2/ TiN@N-C heterostructure by using typical sandwich-like precursors (MXene/ZIF-8). Zerodimensional (0D) TiO2, TiN and N-doped carbon nanoparticles were in situ formed and randomly anchored on the twodimensional (2D) N-doped carbon substrate surface, making TiO2/ TiN@N-C exhibit unique 0D/2D heterostructure. Relative to the extensively studied ZIF-8-derived N-doped carbon nanoparticles, TiO2/ TiN@N-C heterostructure displayed greatly boosted electrochemical active specific surface. Benefiting from the enhanced electrochemical property of TiO2/ TiN@N-C heterostructure, remarkable signal enhancement effect was achieved in terms of the oxidation of multiple hazardous substances, including clozapine, sunset yellow and benomyl. As a result, a novel electrochemical platform was constructed, the linear detection range were 10–1000 nM, 2.5–1250 nM, 10–1000 nM while the detection limits were evaluated to be 3.5 nM, 1.2 nM, 4.5 nM for clozapine, sunset yellow and benomyl, respectively. Besides, the practicability of the newly developed electrochemical method was verified by assessing the content of clozapine, sunset yellow and benomyl in real food samples.

Two-dimensional MXene@ZIF-8 hybrid-derived TiO2TiN@N-C heterostructure as an emerging material for electrochemical sensing
    Abstract
    1 Introduction
    2 Experimental section
        2.1 Synthesis of Ti3C2Tx nanosheets
        2.2 Synthesis of Ti3C2Tx@ZIF-8 hybrids
        2.3 Synthesis of TiO2TiN@N-C heterostructure
        2.4 Pretreatment of real samples
    3 Results and discussion
        3.1 Structure analysis of Ti3C2Tx@ZIF-8 and its derivative TiO2TiN@N-C
        3.2 Electrochemical property of TiO2TiN@N-C materials
        3.3 Electrochemical sensing application
    4 Conclusion
    Acknowledgements 
    References

• Yanhong Zeng(Yueyang Vocational Technical College, Yueyang 414000, China)
• Yong Tang(Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China)
• Mei Liu(College of Health Science and Engineering, Hubei University, Wuhan 430062, China)
• Can Wu(College of Health Science and Engineering, Hubei University, Wuhan 430062, China, Hubei Jiangxia Laboratory, Wuhan 430299, China) Corresponding author