This study investigated the impact of diabetes mellitus (DM) on phacoemulsification outcomes in dogs, focusing on blindness and postoperative complications. A retrospective analysis of 26 dogs (38 eyes) was conducted, comparing diabetic (n=4) and non-diabetic dogs (n=22). Postoperative outcomes were observed for 2 months, and Fisher’s Exact Test was used to assess statistical significance (p<0.05). Blindness occurred in 50% of diabetic eyes compared to 6% in non-diabetic eyes (OR=14.0, p=0.0116). Major complications included glaucoma and retinal detachment, both more common in diabetic dogs. Diabetic dogs are at a significantly higher risk of blindness after phacoemulsification, highlighting the need for thorough preand postoperative management to reduce complications that could lead to vision loss.