In this study, the safety and efficacy of an spot on formulation composed of Fluralaner (40mg/kg)and Moxidectin (2mg/kg) against internal and external parasites was evaluated in Korean cats. The product was developed as a topical use in cats to prevent or control internal and external parasites including ticks, fleas, gastrointestinal parasites, ear mite and heartworm. As a result of the study, targeted for total 30 cats from 8 Korean animal hospitals, this combination of Fluralaner and Moxidectin was found to be very safe in cats, and its effectiveness against external parasites (ticks, fleas, and ear mites) was fully verified. In addition, As the animals exposed in the infective circumstances of heartworm and gastrointestinal parasites were remained negative during the study period of 12 weeks after treatment of test drug, it was determined that this product had a potential preventive effect against the heartworms and gastrointestinal parasites.

Abstract
서 론
재료 및 방법
    참진드기 효능평가(Ixodes Ricinus, Ixodes scapularis,Rhipicephalus sanguineus, Haemaphysalislongicornis 등)
    벼룩 효능평가(Ctenocephalides felis 등)
    귀진드기에 대한 효능 평가(Otodectes cynotis)
    위장관 선충의 치료/예방 효과(Toxocara cati, Ancylostomatubaeforme)
    심장사상충에 대한 예방효과(Dirofilaria immitis)
    안전성 평가: 체중 측정, 임상증상 관찰 및 혈액검사
    통계분석
결 과
    참진드기에 대한 효과
    벼룩 감염에 대한 치료 효과
    귀진드기 감염에 대한 치료효과
    심장사상충증에 대한 예방효과
    안전성 평가 결과
고 찰
REFERENCES

• Su-Jin Park(Department of Animal Health and Welfare, College of Life and Health Science, Hoseo University, Asan 31499, Korea)
• Chang-Hun Lee(Department of Biomedical Laboratory Science, College of Life and Health Science, Hoseo University, Asan 31499, Korea)
• Jeong-Ran Min(Department of Biomedical Laboratory Science, College of Life and Health Science, Hoseo University, Asan 31499, Korea)
• Sang-Hee Jeong(Department of Biomedical Laboratory Science, College of Life and Health Science, Hoseo University, Asan 31499, Korea) Corresponding author