Background: Prolonged use of computers and mobile devices has contributed to postural abnormalities such as Rounded Shoulder Posture (RSP), which is characterized by muscle imbalances that can lead to pain and functional limitations. Correcting these imbalances through targeted stretching and strengthening exercises was expected to help improve postural alignment and muscle function. Objectives: This study aimed to investigate the effects of a six-week integrated exercise program targeting the pectoralis minor (PM), upper trapezius (UT), and lower trapezius (LT) on postural alignment and muscle activation in female adults with RSP. Design: Single-group pre-post test study. Methods: Eighteen female university students (aged 20–22 years) with RSP participated in a six-week intervention consisting of PM stretching, UT stretching, and LT strengthening exercises. RSP severity was assessed using acromion-to-ground distance, PM length was measured with a caliper, and surface electromyography (sEMG) was used to evaluate UT and LT muscle activity. Normality was verified using the Shapiro-Wilk test, and paired t-tests were conducted for statistical analysis (α=0.05). Results: After the intervention, significant improvements were observed in all measured variables. Acromion-to-ground distance decreased (P<0.001), PM length increased (P<0.001), UT activation decreased (P<0.01), and LT activation increased (P<0.01). Conclusion: The six-week integrated exercise program effectively improved postural alignment and muscle activation in women with RSP by addressing muscle shortening, overactivity, and weakness. These findings suggest that combined stretching and strengthening exercises can serve as a practical and effective approach for RSP correction. Future studies with longer durations and diverse populations are recommended to further validate these results and enhance clinical applicability.