담관 주위 담관암 치료는 암의 범위와 공격성에 따른 여러 가지 치료 중에서 절제술과 이식 사이에서 최적의 치료 결과를 위해서 다학제적 접근이 중요하다.

Perihilar cholangiocarcinoma, a rare and aggressive tumor, can develop in the bile ducts at the junction of the right and left hepatic ducts. Successful treatment with of surgical excision and/or transplantation has significantly improved the management of the disease, leading to increased survival rates and better quality of life for patients. Nonetheless, challenges persist, including limited therapy options for advanced-stage disease, potential risks, and a shortage of donor organs. For early-stage disease, surgical resection, usually right hepatectomy, is the preferred treatment, while transplantation is indicated for non-resectable cases. Liver transplantation offers prolonged survival for certain individuals; however, it requires lifelong immunosuppression and carries the risk of recurrence. The choice between resection and transplantation depends on various factors, including disease stage, patient health, and the availability of a donor organ. For patients diagnosed with perihilar cholangiocarcinoma, implementing an interdisciplinary approach is crucial for optimizing therapeutic efficacy.

INTRODUCTION
MANAGEMENT FOR PERIHILARCHOLANGIOCARCINOMA
RESECTION
    1. Patient selection
    2. Neo-adjuvant therapy
    3. Surgical techniques for resection
    4. Reconstruction of the biliary duct
    5. Postoperative management
    6. Adjuvant therapy
    7. Prognosis and outcomes
TRANSPLANTATION
    1. Indications for transplantation
    2. Changing chemotherapy protocols
    3. Radiotherapy targeting the hepatic hilum
    4. Transplantation procedure
    5. Post-transplant management
    6. Recurrence
    7. Outcomes and survival
    8. Postoperative follow-up and adjuvant therapy
COMPARISON OF RESECTION ANDTRANSPLANTATION
    1. Quality of life
CHALLENGES AND FUTURE DIRECTIONS
CONCLUSION
요약
ORCID
FUNDING AND ACKNOWLEDGMENTS
REFERENCES

• 김종만(성균관대학교 의과대학 삼성서울병원 외과학교실) | Jongman Kim (Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea) Corresponding author