Due to recent increase in the number of elderly patients, there is a problem of nutritional imbalance and immune function in the elderly due to decreased ability to consume food. To solve these problems, this study was conducted to verify an immunityenhancing effect of Sagunja-tang porridge (SP) on cyclophosphamide (CPA)-induced immunosuppression using an animal model. Experimental groups were set as normal control, CPA-treated group, positive control group, and SP-treated groups (0.25%, 0.5%, 1.0%). Except for the normal control group, experimental groups were injected with 100 μL of CPA dissolved in 0.9% NaCl at a concentration of 150 mg/kg twice at the beginning of the experiment and 3 days later to induce immunosuppression. When spleen cell proliferation was analyzed, both B and T cells were decreased in the immunosuppressed group, but increased in test substance-treated groups in a concentration-dependent manner. To see the effect of improving immunity, levels of IgA known to protect the mucosal surface were measured. Higher levels of IgA were found in SP-low concentration (SL) and SP-middle concentration (SM) groups. These results suggest that using SP might be an effective way to improve nutritional imbalance and immune function in the elderly.

Abstract
서 론
재료 및 방법
    1. 사군자탕 죽의 제조
    2. 실험동물
    3. 동물군 설정 및 투여
    4. 장기 중량 측정
    5. 일반 혈액 검사
    6. 비장세포 증식능 측정
    7. 림프구 아형 검사
    8. 면역글로불린 측정
    9. 조직병리학적 검사
    10. 통계분석
결과 및 고찰
    1. 동물의 체중 변화
    2. 장기 중량 측정
    3. 일반 혈액 검사
    4. 비장세포 증식능 측정
    5. 림프구 아형 검사
    6. 면역글로불린 검사
    7. 조직병리학적 검사
요약 및 결론
References

• 백승화(대전대학교 대학원 임상병리학과 대학원생) | Seung-Hwa Baek (Graduate School Student, Department of Biomedical Laboratory Science, Daejeon University, Daejeon 34520, Korea)
• 서희원(대전대학교 대학원 임상병리학과 대학원생) | Hee Won Seo (Graduate School Student, Department of Biomedical Laboratory Science, Daejeon University, Daejeon 34520, Korea)
• 오지혜(대전대학교 대학원 임상병리학과 박사) | Ji-Hye Oh (Doctor, Dept. of Biomedical Laboratory Science, Daejeon University, Daejeon 34520, Korea)
• 최학주(대전대학교 한의학과 본초학교실 교수) | Hak-Joo Choi (Professor, Dept. of Herbology, Collge of Korean Medicine, Daejeon University, Daejeon 34520, Korea)
• 황석연(대전대학교 임상병리학과 혈액조직학교실 교수) | Seock-Yeon Hwang (Professor, Dept. of Biomedical Laboratory Science, Daejeon University, Daejeon 34520, Korea) Corresponding author