This study examined the impact of Artemisia argyi extract (AE) on bone health using a mouse model of ovariectomy (OVX)-induced osteoporosis. A total of seven sham-operated mice and twenty-one OVX mice were assigned to three groups: control (OVX), estradiol-treated (E2, 10 μg/kg), and AE-treated (100 mg/kg). The treatment lasted for 12 weeks, during which body weight, food intake, hindlimb thickness, grip strength, and various bone parameters were recorded. Dual-energy X-ray absorptiometry (DXA) was employed to evaluate body composition, bone mineral content (BMC), and bone mineral density (BMD). The administration of AE significantly increased BMC and BMD compared to the OVX group, with no notable changes in body composition. Although AE did not enhance hindlimb thickness, it did significantly improve grip strength. These findings indicate that AE selectively promotes bone metabolism and may serve as a potential functional food component for preventing osteoporosis in postmenopausal women.

Abstract
서 론
재료 및 방법
    1. 실험동물 및 사육 조건
    2. Artemisia argyi extract 준비
    3. 체중, 식이섭취량 측정 및 시료 수집
    4. 혈장 지질 농도 분석
    5. 허벅지 근육 두께 및 인장력 측정
    6. 체성분 및 골밀도 분석(DXA)
    7. 통계 분석
결과 및 고찰
    1. 체중 변화 및 식이섭취량
    2. 혈중 지질 농도
    3. 조직 무게
    4. 허벅지 근육 두께 및 인장력
    5. 골무기질량 및 골밀도
요약 및 결론
감사의 글
References

• 정지원(경북대학교 식품영양학과 대학원생) | Jiwon Jeong (Graduate Student, Dept. of Food Science and Nutrition, Kyungpook National University, Daegu 41566, Korea)
• 권은영(경북대학교 식품영양학과 교수) | Eun-Young Kwon (Professor, Dept. of Food Science and Nutrition, Center for Food and Nutritional Genomics Research, Center for Beautiful Aging, Dept. of Advanced Bioconvergence, Kyungpook National University, Daegu 41566, Korea)
• 김도연(경북대학교 식품영양학과 학사) | Kim Doyeon (Bachelor's Degree, Dept. of Food Science and Nutrition, Kyungpook National University, Daegu 41566, Korea)
• 신수경(경북대학교 식품영양유전체 연구센터 연구교수) | Su-Kyung Shin (Research Professor, Center for Food and Nutritional Genomics Research, Kyungpook National University, Daegu 41566, Korea) Corresponding author