Sunblocks are materials used in creams to help limit exposure to UVA and UVB. Many sunscreens contain TiO2 and ZnO as the primary sunblock materials. In this study, we manufactured a sunscreen lotion using hydroxyapatite (HAp) nano-sol instead of ZnO and TiO2. HAp is a biomaterial widely used in applications such as bone grafting, so it is known to be very biocompatible. In the present work, HAp-water nano sol, ZnO-water nano sol, and TiO2-water nano sol were prepared by the attrition milling method. The sunscreen lotion base (LB) was manufactured with some oil and water. Lotions with various HAp-water solutions and LB concentrations were fabricated and their UV absorbance was measured. 6 % HAp content was the optimal amount considering price. The sun protection factor (SPF) value at that level was approximately 20 on average, corresponding to about 95 % UV protection. Results confirmed that ultraviolet screening agents using HAp had an excellent ultraviolet blocking effect.